Articles tagged with: HIV

Aug20

An ArcGIS Mapping Tool to Identify MPT Target Populations

Tuesday, 20 August 2019 Written by // Kyli Gallington Tags // contraceptive, GIS mapping, HIV, women

In sub-Saharan Africa, adolescent girls and young women are at the highest risk of acquiring HIV. However, as this is a heterogeneous population, the characteristics of these women can vary greatly. A one-size-fits-all approach simply will not work. In order for MPTs to have the greatest impact, approaches must be tailored to the populations where they are most likely to be successful.

Jun20

MEET THE SECRETARIAT STAFF | Laura Dellplain, Project Manager

Thursday, 20 June 2019 Written by // Laura Dellplain Series // Meet the Secretariat Staff Tags // development, HIV, prevention

As an HIV tester and counselor during my university days and beyond, I learned very quickly that most people have more pressing issues to deal with in their lives than HIV prevention. At at Oberlin College, I often saw clients shortly after an unprotected sexual encounter. For most, condom use to protect against HIV and other STIs had to be negotiated alongside myriad influential experiences and other barriers – including insecurity around the sexual relationship, fear around the sexual encounter, school stress, mental illness, and financial hardship, just to name a few. The very fact that these clients had proactively sought out an HIV test, demonstrated to me that they were both aware of and concerned about HIV risk, but that the prevention methods available to them just did not meet their needs or circumstances.

Dec01

IMPT Advisory Council: Pioneers for an HIV-free world and more

Saturday, 01 December 2018 Tags // advisory council, HIV, prevention, product choices, women, World AIDS Day

Every four minutes, three young women will become infected with HIV—that’s close to 900,000 new infections a year. While HIV prevention research and drug development have progressed rapidly, there is still work to be done. This World AIDS Day, we reflect on our work to advance MPTs by asking the IMPT Advisory Council for their perspective on the role of MPTs in the fight to end the HIV epidemic.

Oct17

FROM THE PIPELINE | Monoclonal antibodies as future MPT products

Wednesday, 17 October 2018 Written by // Kevin Whaley Series // From the Pipeline Tags // contraceptive, HIV, manufacturing, monoclonal antibodies

Monoclonal antibodies are engineered proteins derived from a single parent cell and have been used in a diverse range of therapeutic applications due to their versatility and specificity. At Mapp Biopharmaceutical, Inc., we believe monoclonal antibodies are promising candidates for multipurpose prevention technologies (MPTs) when formulated as topical (e.g., films and rings) or injectable products. Systemic antibodies may have multiple effector functions – like complement binding (CDC) and binding to monocytes (ADCC) – while mucosal mechanisms agglutination and trapping in mucus are less widely discussed, but are crucial for the protection of mucosal surfaces. Systemically and mucosally delivered antibodies have demonstrated efficacy in SHIV prevention studies. In this post, we describe some of the important progress to date on monoclonal antibodies as future MPTs.

Oct16

Young people are leading the charge of the HIV prevention movement

Tuesday, 16 October 2018 Written by // Erin McKelle Tags // HIV, prevention, young people, youth

HIV prevention has come to the forefront of youth activism and public health advocacy, as young people aged 15-24 account for 35% of new HIV infections worldwide. In fact, as we work to curb the HIV epidemic, they are the only age group to experience a recent increase in HIV infections. Young people are disproportionately impacted by HIV and face unique challenges in protecting their sexual health as they navigate complex biological and social transitions into adulthood. In that spirit, the FDA recently approved PrEP (Pre-Exposure Prophylaxis) for adolescents, which has huge implications for empowering young people to prevent HIV exposure or transmission.

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