Articles tagged with: intravaginal ring

Aug01

FROM THE PIPELINE | Taking on a challenge – How an ambitious engineering goal led to an innovative MPT for HIV, HSV, and unintended pregnancy

Wednesday, 01 August 2018 Written by // Meredith Roberts Clark, Kathleen Dietz Series // From the Pipeline Tags // challenge, clinical study, intravaginal ring, women

It all started with the simple realization that women seeking protection against HIV also want to prevent unintended pregnancies. In general, they also prefer a combined method. Then followed the innovation challenge: Engineer a long-acting intravaginal ring that could release two chemically diverse drugs – one for HIV and herpes simplex virus (HSV) prevention, and one for contraception – at sustained, controlled, and yet extremely different release rates (up to 1000-fold) for 3 months; make it suitable and scalable for use in resource-limited countries, such as those of sub-Saharan Africa; and design it so women would want to use it. Even now it’s a daunting task. When this project began, 10 years ago, its feasibility was questioned by many, including our collaborators and ourselves. However, if successful, this challenge had strong potential to provide a truly game-changing MPT solution to a dire unmet need for women globally.

Recent Posts

Any thoughts? Contact us to learn more about the submission process.

Share

Spread the word about the promise of MPTs.

Collaborate

We will go further together – join the movement for MPTs.

Contribute

Your financial and in-kind support can help make MPTs a reality.